We are proud to highlight the accomplishment of Dr. Matthew Regulski, who has contributed his expertise as a co-author in the recently published paper “A Synergistic Multimodality Treatment Approach to Address the Key Drivers of Wound Chronicity.” PubMed+1 Why this matters Chronic wounds – such as those seen in patients with diabetes, vascular issues, or persistent edema – remain a major clinical and economic burden worldwide. PubMed+1 The new article reviews key drivers of wound non-healing: hypoxia (low oxygen), unresolved inflammation, edema/lymphatic dysfunction, endothelial injury, and reperfusion stress. PubMed+1 The authors then evaluate a combined therapy approach: topical oxygen therapy (TOT) plus intermittent compression (IC) – together called intermittent topical oxygen therapy (ITOT) – which works to simultaneously address multiple underlying mechanisms. ScienceDirect+1 Their conclusion: these modalities used together can produce synergistic benefits, improving healing rates, reducing healing time, lowering recurrence and hospitalizations, and offering cost-effectiveness. PubMed Dr. Regulski’s role Dr. Regulski, medical director of the Wound Care Institute of Ocean County, NJ, and senior partner at Ocean County Foot & Ankle Surgical Associates, brings extensive clinical experience in limb salvage, diabetic foot reconstruction, and wound healing research. WoundSource+1 His co-authorship in this cutting-edge study emphasizes his commitment to advancing wound care science and applying evidence-based treatments to improve patient outcomes. Implications for our team and patients This represents a meaningful opportunity to incorporate emerging therapies into our wound-care protocols. Some key takeaways: Recognizing that chronic wounds rarely have a single barrier to healing — so multifactorial approaches matter Emphasizing early intervention to break the persistent hypoxia/inflammation/edema cycle Considering adjunctive therapies (such as topical oxygen + compression) in cases that are refractory to standard care Ensuring our team is up-to-date on the latest research and has pathways to translate evidence into practice Looking ahead  Our commitment is to translate research into excellence in patient-care. We congratulate Dr. Regulski on this achievement and look forward to supporting wider adoption of these concepts in our practices. For patients experiencing non-healing foot or lower extremity wounds, we encourage engagement with our wound-care specialists who are equipped to evaluate advanced therapies when appropriate. Full Study Link: https://www.jvsvenous.org/article/S2213-333X(25)00183-0/fulltext

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