Radiation therapy is commonly employed in the treatment of various cancers alone, or in a combination with surgical tumor excision, with the purpose of selectively killing cancer cells at the tumor site.1 Radiation therapy, however, is damaging to the surrounding healthy tissue and may result in tissue necrosis. Radiation can also compromise wound healing leading…
Diabetic foot ulcers (DFUs), venous leg ulcers (VLUs), and pressure ulcers (PUs) represent the most common hard-to-heal wounds. According to Armstrong, “Every 1.2 seconds, someone develops a diabetic ulcer; every 20 seconds, someone is amputated.” In the United States, $1 million is spent every 30 seconds on diabetic foot complications. The news is similar for…
All wounds, especially chronic ones, become colonized with bacteria. It arises from the patient’s skin, respiratory tract, gastrointestinal tract, or where exogenous bacteria are transferred from the environment or conveyed on the hands of healthcare workers [1-3]. When the bacterial load reaches 105 CFU/G, which is colony forming units per gram of tissue, the wound…
Arthrodesis of the first metatarsal-phalangeal joint is a reliable procedure for correction of both hallux limitus/rigidus and severe hallux abducto valgus deformities (1). However, one potential contraindication to the procedure is the extended period of non-weight-bearing immobilization that is typically associated with the postoperative course. The objective of this investigation was to perform a systematic…
The evolution of stem cells in the chronic wound regimen has taken a very circuitous path, so to speak. This article will briefly describe some of the different types of stem cells and how they may be utilized as therapeutic modalities in healthcare, including specifically in wound care. TYPES OF STEM CELLS When we talk…
Although the effect of lower extremity pathology and surgical intervention on automobile driving function has been a topic of contemporary interest, we are unaware of any analysis of the effect of lower extremity diabetic sensorimotor neuropathy on driving performance. The objective of the present case-control investigation was to assess the mean brake response time in…
The objective of the present investigation was to evaluate the published scientific data with respect to the diabetic foot. We specifically aimed to assess the quantity published and the specific location of the published reports. A standard PubMed® search was performed, and the returned abstracts were evaluated by a 2-person panel for their relevance to…
Biochemical properties of the amniotic membrane help modulate inflammation and enhance soft-tissue healing. In controlled trials, the efficacy of dehydrated human amnion/chorion membrane (dHACM) allografts has been established. Our purpose is to describe our experience with using dHACM to treat nonhealing wounds of various etiologies…
Superficial acral fibromyxoma is a benign and slow-growing solitary soft-tissue neoplasm. Since being described in 2001, more than 100 cases of superficial acral fibromyxoma on the foot have been reported worldwide, none of which have been reported in the podiatric medical literature. Only nine cases of superficial acral fibromyxoma have been reported with presentation on…
We have previously demonstrated an abnormally delayed mean brake response time and an increased frequency of abnormally delayed brake responses in a group of neuropathic drivers with diabetes compared with a control group of drivers with neither diabetes nor lower extremity neuropathy. The objective of the present case-control study was to compare the mean brake…